Sychem Bio-Decontamination Services


The control of microbiological contamination is necessary to ensure that production and research meet the requested parameters of quality and safety. To maintain the required conditions and avoid the risk of microbial contaminations, periodical VPHP bio-decontamination cycles should be carried out. Sychem Bio-decontamination Services uses Vapor-Phase Hydrogen Peroxide (VPHP) by Bioreset as a cold sterilising agent.

 Sychem Bio-Decontamination Services for the Healthcare and Life Science

Bio-decontamination Services

The VPHP is lethal to all known microorganisms and chemically active against spores with proven kill rates, achieving full 6-Log reduction and offering higher levels of safety compared to other gaseous agents. Our Bio-decontamination Services remove the airborne and surface microbiological contamination that affects controlled or classified environments, such as pharmaceutical, biomedical, biotechnological, animal care, health care and any other environment sensitive to microbiological contamination.

Sychem offers a complete package of on site Bio-decontamination Services. The VPHP decontamination process resets the environment from microbiological contamination, ensuring a broad antimicrobial spectrum by reaching any surface exposed to the dry vapor.

The validation service is executed with a chemical indicator map to verify the correct distribution and microbiological indicator map (with Bacillus Stearothermophilus spores) to prove the cycle efficacy. Biological indicators are incubated at 55°C as described in the international guidelines.

The monitor service is executed with appropriate instrumentation, to check the residual Hydrogen Peroxide based on international guidelines of < 1 ppm. The whole Bio-decontamination process is managed with confidence from start to finish by specialist personnel with years of experience in decontamination services.

site evaluation

Sychem engineers will have an initial project meeting to identify all the client's requirement and define all the areas that need decontamination. A risk assessment and method statement will follow the the initial step to provide the client with a comprehensive explanation of the project and schedule of all the stages of the decontamination process, ensuring maximum clarity and safety.


Sychem engineers will prepare the rooms to be decontaminated by placing throughout the chemical and biological indicators that will help to establish the success of the decontamination. once the areas has been prepared for the decontamination, the VPHP generators will start the cycles that end automatically once the decontamination program is finished.


The data and results provided by the chemical and biological indicators are then collected and verified to supply the client with a full documented test report of the decontamination cycle. After the validation review meeting, the client is provided with the certificate of biodecontamination, which state the success of the operation.